, 2014, Yang, et al., 2012). The activity of NKA in brain can be downregulated by phosphorylation of the subunit at Ser23 by PKC or Ser943 by PKA (Yang, et al., 2012). Changes in NKA expression in the ICH brain have not been reported. Immunoblotting results showed that the expression of NKA 1 subunit and PKA-dependent phosphorylation at Ser943 did not change significantly in progesterone-treated