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Ce were fed Purina Chow until ten wk of age, and then fed western diet regime (Teklad 88137, Harlan Teklad) for the subsequent 8 wk. Mice were fasted overnight prior to they had been killed. Their tissues have been collected, flash frozen in liquid nitrogen, and stored in 280uC before RNA isolation. RNA preparation and array hybridizations have been performed at Rosetta Inpharmatics. The custom in