In ABO) explained 25 of variance of blood E-selectin (SELE) in SPIROMICS and 27 of variance in COPDGene (Fig six). In lots of circumstances, pQTL SNPs explained far more variance inside the quantitative biomarker than did clinical covariates. To assess the novelty of these pQTL SNPs, we cross-referenced the exceptional 478 pQTL SNPs we identified with SNPs connected with any published GWAS based